Profiling protein expression in circulating tumour cells using microfluidic western blotting.
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ABSTRACT:
SUBMITTER: Sinkala E
PROVIDER: S-EPMC5376644 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Publications
Profiling protein expression in circulating tumour cells using microfluidic western blotting.
Sinkala Elly E Sollier-Christen Elodie E Renier Corinne C Rosàs-Canyelles Elisabet E Che James J Heirich Kyra K Duncombe Todd A TA Vlassakis Julea J Yamauchi Kevin A KA Huang Haiyan H Jeffrey Stefanie S SS Herr Amy E AE
Nature communications 20170323
Circulating tumour cells (CTCs) are rare tumour cells found in the circulatory system of certain cancer patients. The clinical and functional significance of CTCs is still under investigation. Protein profiling of CTCs would complement the recent advances in enumeration, transcriptomic and genomic characterization of these rare cells and help define their characteristics. Here we describe a microfluidic western blot for an eight-plex protein panel for individual CTCs derived from estrogen recept ...[more]
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