Ontology highlight
ABSTRACT:
SUBMITTER: Potkin SG
PROVIDER: S-EPMC5378005 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Potkin Steven G SG Loze Jean-Yves JY Forray Carlos C Baker Ross A RA Sapin Christophe C Peters-Strickland Timothy T Beillat Maud M Nylander Anna-Greta AG Hertel Peter P Steen Andersen Henrik H Eramo Anna A Hansen Karina K Naber Dieter D
International clinical psychopharmacology 20170501 3
Sexual dysfunction, a common side effect of antipsychotic medications, may be partly caused by dopamine antagonism and elevation of prolactin. In QUALIFY, a randomized study, aripiprazole once-monthly 400 mg (AOM 400), a dopamine D2 receptor partial agonist, showed noninferiority and subsequent superiority versus paliperidone palmitate (PP), a dopamine D2 receptor antagonist, on the Heinrichs-Carpenter Quality-of-Life Scale (QLS) in patients with schizophrenia aged 18-60 years. Sexual dysfunctio ...[more]