Ontology highlight
ABSTRACT:
SUBMITTER: Veldhuis JH
PROVIDER: S-EPMC5379031 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Veldhuis Jim H JH Ehsandar Ahmad A Maître Jean-Léon JL Hiiragi Takashi T Cox Simon S Brodland G Wayne GW
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20170501 1720
Although the importance of cellular forces to a wide range of embryogenesis and disease processes is widely recognized, measuring these forces is challenging, especially in three dimensions. Here, we introduce CellFIT-3D, a force inference technique that allows tension maps for three-dimensional cellular systems to be estimated from image stacks. Like its predecessors, video force microscopy and CellFIT, this cell mechanics technique assumes boundary-specific interfacial tensions to be the prima ...[more]