Ontology highlight
ABSTRACT:
SUBMITTER: Schuabb C
PROVIDER: S-EPMC5379106 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Schuabb Caroline C Kumar Narendra N Pataraia Salome S Marx Dominik D Winter Roland R
Nature communications 20170330
The ability of certain RNAs, denoted as ribozymes, to not only store genetic information but also catalyse chemical reactions gave support to the RNA world hypothesis as a putative step in the development of early life on Earth. This, however, might have evolved under extreme environmental conditions, including the deep sea with pressures in the kbar regime. Here we study pressure-induced effects on the self-cleavage of hairpin ribozyme by following structural changes in real-time. Our results s ...[more]