Ontology highlight
ABSTRACT:
SUBMITTER: Wittmann S
PROVIDER: S-EPMC5382271 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Wittmann Sina S Renner Max M Watts Beth R BR Adams Oliver O Huseyin Miles M Baejen Carlo C El Omari Kamel K Kilchert Cornelia C Heo Dong-Hyuk DH Kecman Tea T Cramer Patrick P Grimes Jonathan M JM Vasiljeva Lidia L
Nature communications 20170403
Termination of RNA polymerase II (Pol II) transcription is an important step in the transcription cycle, which involves the dislodgement of polymerase from DNA, leading to release of a functional transcript. Recent studies have identified the key players required for this process and showed that a common feature of these proteins is a conserved domain that interacts with the phosphorylated C-terminus of Pol II (CTD-interacting domain, CID). However, the mechanism by which transcription terminati ...[more]