Ontology highlight
ABSTRACT:
SUBMITTER: Yu X
PROVIDER: S-EPMC538561 | biostudies-literature | 2005 Jan
REPOSITORIES: biostudies-literature
Yu Xuekui X Shah Sanket S Atanasov Ivo I Lo Pierrette P Liu Fenyong F Britt William J WJ Zhou Z Hong ZH
Journal of virology 20050101 2
The smallest capsid proteins (SCPs) of the human herpesviruses differ substantially in size and sequence and are thought to impart some unique aspects of infection to their respective viruses. We used electron cryomicroscopy and antibody labeling to show that the 8-kDa SCP of human cytomegalovirus is attached only to major capsid protein subunits of the hexons, not the pentons. Thus, the SCPs of different herpesviruses illustrate that a protein can evolve significantly in sequence, structure, an ...[more]