Ontology highlight
ABSTRACT:
SUBMITTER: Skjoldager N
PROVIDER: S-EPMC5387739 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Scientific reports 20170411
The NADPH-dependent homodimeric flavoenzyme thioredoxin reductase (TrxR) provides reducing equivalents to thioredoxin, a key regulator of various cellular redox processes. Crystal structures of photo-inactivated thioredoxin reductase (TrxR) from the Gram-positive bacterium Lactococcus lactis have been determined. These structures reveal novel molecular features that provide further insight into the mechanisms behind the sensitivity of this enzyme toward visible light. We propose that a pocket on ...[more]