Ontology highlight
ABSTRACT:
SUBMITTER: Gershlak JR
PROVIDER: S-EPMC5388455 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Gershlak Joshua R JR Hernandez Sarah S Fontana Gianluca G Perreault Luke R LR Hansen Katrina J KJ Larson Sara A SA Binder Bernard Y K BY Dolivo David M DM Yang Tianhong T Dominko Tanja T Rolle Marsha W MW Weathers Pamela J PJ Medina-Bolivar Fabricio F Cramer Carole L CL Murphy William L WL Gaudette Glenn R GR
Biomaterials 20170210
Despite significant advances in the fabrication of bioengineered scaffolds for tissue engineering, delivery of nutrients in complex engineered human tissues remains a challenge. By taking advantage of the similarities in the vascular structure of plant and animal tissues, we developed decellularized plant tissue as a prevascularized scaffold for tissue engineering applications. Perfusion-based decellularization was modified for different plant species, providing different geometries of scaffoldi ...[more]