Ontology highlight
ABSTRACT:
SUBMITTER: Yi J
PROVIDER: S-EPMC5389685 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Yi Jia J Shen Hai-Feng HF Qiu Jin-Song JS Huang Ming-Feng MF Zhang Wen-Juan WJ Ding Jian-Cheng JC Zhu Xiao-Yan XY Zhou Yu Y Fu Xiang-Dong XD Liu Wen W
Nucleic acids research 20170401 6
JMJD6, a jumonji C (Jmj C) domain-containing protein demethylase and hydroxylase, has been implicated in an array of biological processes. It has been shown that JMJD6 interacts with and hydroxylates multiple serine/arginine-rich (SR) proteins and SR related proteins, including U2AF65, all of which are known to function in alternative splicing regulation. However, whether JMJD6 is widely involved in alternative splicing and the molecular mechanism underlying JMJD6-regulated alternative splicing ...[more]