Ontology highlight
ABSTRACT:
SUBMITTER: Gumienny R
PROVIDER: S-EPMC5389715 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Gumienny Rafal R Jedlinski Dominik J DJ Schmidt Alexander A Gypas Foivos F Martin Georges G Vina-Vilaseca Arnau A Zavolan Mihaela M
Nucleic acids research 20170301 5
High-throughput sequencing has greatly facilitated the discovery of long and short non-coding RNAs (ncRNAs), which frequently guide ribonucleoprotein complexes to RNA targets, to modulate their metabolism and expression. However, for many ncRNAs, the targets remain to be discovered. In this study, we developed computational methods to map C/D box snoRNA target sites using data from core small nucleolar ribonucleoprotein crosslinking and immunoprecipitation and from transcriptome-wide mapping of ...[more]