Ontology highlight
ABSTRACT:
SUBMITTER: Park S
PROVIDER: S-EPMC5390092 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Stem cell reports 20170119 4
Sickle cell anemia affects millions of people worldwide and is an emerging global health burden. As part of a large NIH-funded NextGen Consortium, we generated a diverse, comprehensive, and fully characterized library of sickle-cell-disease-specific induced pluripotent stem cells (iPSCs) from patients of different ethnicities, β-globin gene (HBB) haplotypes, and fetal hemoglobin (HbF) levels. iPSCs stand to revolutionize the way we study human development, model disease, and perhaps eventually, ...[more]