Polymeric Materials for Gene Delivery and DNA Vaccination.
Ontology highlight
ABSTRACT:
SUBMITTER: Nguyen DN
PROVIDER: S-EPMC5391878 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Publications
Polymeric Materials for Gene Delivery and DNA Vaccination.
Nguyen David N DN Green Jordan J JJ Chan Juliana M JM Longer Robert R Anderson Daniel G DG
Advanced materials (Deerfield Beach, Fla.) 20081204 8
Gene delivery holds great potential for the treatment of many different diseases. Vaccination with DNA holds particular promise, and may provide a solution to many technical challenges that hinder traditional vaccine systems including rapid development and production and induction of robust cell-mediated immune responses. However, few candidate DNA vaccines have progressed past preclinical development and none have been approved for human use. This Review focuses on the recent progress and chall ...[more]
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