Ontology highlight
ABSTRACT:
SUBMITTER: Vestergaard ET
PROVIDER: S-EPMC5393419 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Vestergaard Esben Thyssen ET Buhl Mads M Gjedsted Jakob J Madsen Michael M Jessen Niels N Nielsen Soren S Gaylinn Bruce D BD Liu Jianhua J Thorner Michael O MO Moller Niels N Jorgensen Jens Otto Lunde JO
The Journal of clinical endocrinology and metabolism 20101117 2
<h4>Context</h4>Ghrelin is the endogenous agonist for the growth hormone secretagogue receptor (GHS-R). Intravenous administration of ghrelin induces insulin resistance and hyperglycemia and increases the levels of free fatty acids (FFA).<h4>Objective</h4>To investigate whether these effects are mediated directly by ghrelin in skeletal muscle tissue.<h4>Design</h4>This study was single blinded, randomized, and placebo controlled. Eight healthy men (25.5 ± 3.1 years) received 240 min of intraarte ...[more]