Ontology highlight
ABSTRACT:
SUBMITTER: Lih CJ
PROVIDER: S-EPMC5397672 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Lih Chih-Jian CJ Harrington Robin D RD Sims David J DJ Harper Kneshay N KN Bouk Courtney H CH Datta Vivekananda V Yau Jonathan J Singh Rajesh R RR Routbort Mark J MJ Luthra Rajyalakshmi R Patel Keyur P KP Mantha Geeta S GS Krishnamurthy Savitri S Ronski Karyn K Walther Zenta Z Finberg Karin E KE Canosa Sandra S Robinson Hayley H Raymond Amelia A Le Long P LP McShane Lisa M LM Polley Eric C EC Conley Barbara A BA Doroshow James H JH Iafrate A John AJ Sklar Jeffrey L JL Hamilton Stanley R SR Williams P Mickey PM
The Journal of molecular diagnostics : JMD 20170207 2
The National Cancer Institute-Molecular Analysis for Therapy Choice (NCI-MATCH) trial is a national signal-finding precision medicine study that relies on genomic assays to screen and enroll patients with relapsed or refractory cancer after standard treatments. We report the analytical validation processes for the next-generation sequencing (NGS) assay that was tailored for regulatory compliant use in the trial. The Oncomine Cancer Panel assay and the Personal Genome Machine were used in four ne ...[more]