Ontology highlight
ABSTRACT:
SUBMITTER: Nguyen V
PROVIDER: S-EPMC5397725 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Nguyen Vanloan V Mendelsohn Andrew A Larrick James W JW
Journal of immunology research 20170406
The age of an individual is an important, independent risk factor for many of the most common diseases afflicting modern societies. Interleukin-7 (IL-7) plays a central, critical role in the homeostasis of the immune system. Recent studies support a critical role for IL-7 in the maintenance of a vigorous healthspan. We describe the role of IL-7 and its receptor in immunosenescence, the aging of the immune system. An understanding of the role that IL-7 plays in aging may permit parsimonious preve ...[more]