Ontology highlight
ABSTRACT:
SUBMITTER: Waaijer MEC
PROVIDER: S-EPMC6612632 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Waaijer Mariëtte E C MEC Goldeck David D Gunn David A DA van Heemst Diana D Westendorp Rudi G J RGJ Pawelec Graham G Maier Andrea B AB
Aging cell 20190506 4
With advancing age, many organs exhibit functional deterioration. The age-associated accumulation of senescent cells is believed to represent one factor contributing to this phenomenon. While senescent cells are found in several different organ systems, it is not known whether they arise independently in each organ system or whether their prevalence within an individual reflects that individual's intrinsic aging process. To address this question, we studied senescence in two different organ syst ...[more]