Ontology highlight
ABSTRACT:
SUBMITTER: DeMarco KR
PROVIDER: S-EPMC5398315 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Current topics in membranes 20160614
Heart rhythms arise from electrical activity generated by precisely timed opening and closing of ion channels in individual cardiac myocytes. Opening of the primary cardiac voltage-gated sodium (NaV1.5) channel initiates cellular depolarization and the propagation of an electrical action potential that promotes coordinated contraction of the heart. The regularity of these contractile waves is critically important since it drives the primary function of the heart: to act as a pump that delivers b ...[more]