Making urothelial carcinomas less immune to immunotherapy.
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ABSTRACT:
SUBMITTER: Ramos JD
PROVIDER: S-EPMC5402727 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Publications
Making urothelial carcinomas less immune to immunotherapy.
Urologic oncology 20161108 12
The success of immune checkpoint inhibitors in advanced urothelial carcinoma provides patients with the prospect for durable objective responses. However, the majority of patients do not respond to immune checkpoint blockade. Several potential predictive biomarkers of response have been evaluated in hopes of better identifying likely responders, though each has been shown to have limitations. Going forward, development of reliable predictive biomarkers is imperative. Likewise, innovative treatme ...[more]
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