Ontology highlight
ABSTRACT:
SUBMITTER: Zheng C
PROVIDER: S-EPMC5404510 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Zheng Changbo C Lo Chun-Yin CY Meng Zhaoyue Z Li Zhichao Z Zhong Mingkui M Zhang Peng P Lu Jun J Yang Zhaoxiang Z Yan Fuman F Zhang Yunting Y Huang Yu Y Yao Xiaoqiang X
Frontiers in pharmacology 20170425
Cardiac hypertrophy is a major risk factor for heart failure, which are among the leading causes of human death. Gastrodin is a small molecule that has been used clinically to treat neurological and vascular diseases for many years without safety issues. In the present study, we examined protective effect of gastrodin against cardiac hypertrophy and explored the underlying mechanism. Phenylephrine and angiotensin II were used to induce cardiac hypertrophy in a mouse model and a cultured cardiomy ...[more]