Ontology highlight
ABSTRACT:
SUBMITTER: Zhong H
PROVIDER: S-EPMC5404597 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Zhong Hua H Hu Dan-Dan DD Hu Gan-Hai GH Su Juan J Bi Shuang S Zhang Zhuo-Er ZE Wang Zheng Z Zhang Ri-Li RL Xu Zheng Z Jiang Yuan-Ying YY Wang Yan Y
Antimicrobial agents and chemotherapy 20170424 5
<i>Candida albicans</i> biofilms show resistance to many clinical antifungal agents and play a considerable contributing role in the process of <i>C. albicans</i> infections. New antifungal agents against <i>C. albicans</i> biofilms are sorely needed. The aim of this study was to evaluate sanguinarine (SAN) for its activity against <i>Candida albicans</i> biofilms and explore the underlying mechanism. The MIC<sub>50</sub> of SAN was 3.2 μg/ml, while ≥0.8 μg/ml of SAN could suppress <i>C. albican ...[more]