Ontology highlight
ABSTRACT:
SUBMITTER: Engeln M
PROVIDER: S-EPMC5405054 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Neuropharmacology 20160520
Impulse control disorders (ICDs) are debilitating side effects of dopamine replacement therapy (DRT) in Parkinson's disease (PD) that severely affect the quality of life of patients. While DRT, the pattern and extent of neurodegeneration, and prodromic factors of vulnerability (e.g. impulsivity) have all been hypothesized to play a role in the development of ICDs, their respective, and potentially interacting, contributions remain to be established. High impulsive (HI), Intermediate (Int) or low ...[more]