Ontology highlight
ABSTRACT:
SUBMITTER: Hsu CW
PROVIDER: S-EPMC5405732 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Hsu Chih-Wei CW Wong Leeyean L Rasmussen Tara L TL Kalaga Sowmya S McElwee Melissa L ML Keith Lance C LC Bohat Ritu R Seavitt John R JR Beaudet Arthur L AL Dickinson Mary E ME
Developmental biology 20160923 2
In this work, we report the use of iodine-contrast microCT to perform high-throughput 3D morphological analysis of mouse embryos and neonates between embryonic day 8.5 to postnatal day 3, with high spatial resolution up to 3µm/voxel. We show that mouse embryos at early stages can be imaged either within extra embryonic tissues such as the yolk sac or the decidua without physically disturbing the embryos. This method enables a full, undisturbed analysis of embryo turning, allantois development, v ...[more]