Ontology highlight
ABSTRACT:
SUBMITTER: Mohimani H
PROVIDER: S-EPMC5409158 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Mohimani Hosein H Gurevich Alexey A Mikheenko Alla A Garg Neha N Nothias Louis-Felix LF Ninomiya Akihiro A Takada Kentaro K Dorrestein Pieter C PC Pevzner Pavel A PA
Nature chemical biology 20161031 1
Peptidic natural products (PNPs) are widely used compounds that include many antibiotics and a variety of other bioactive peptides. Although recent breakthroughs in PNP discovery raised the challenge of developing new algorithms for their analysis, identification of PNPs via database search of tandem mass spectra remains an open problem. To address this problem, natural product researchers use dereplication strategies that identify known PNPs and lead to the discovery of new ones, even in cases ...[more]