Ontology highlight
ABSTRACT:
SUBMITTER: Mohimani H
PROVIDER: S-EPMC6168521 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Mohimani Hosein H Gurevich Alexey A Shlemov Alexander A Mikheenko Alla A Korobeynikov Anton A Cao Liu L Shcherbin Egor E Nothias Louis-Felix LF Dorrestein Pieter C PC Pevzner Pavel A PA
Nature communications 20181002 1
Natural products have traditionally been rich sources for drug discovery. In order to clear the road toward the discovery of unknown natural products, biologists need dereplication strategies that identify known ones. Here we report DEREPLICATOR+, an algorithm that improves on the previous approaches for identifying peptidic natural products, and extends them for identification of polyketides, terpenes, benzenoids, alkaloids, flavonoids, and other classes of natural products. We show that DEREPL ...[more]