Ontology highlight
ABSTRACT:
SUBMITTER: Geillon F
PROVIDER: S-EPMC5409465 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Geillon Flore F Gondcaille Catherine C Raas Quentin Q Dias Alexandre M M AMM Pecqueur Delphine D Truntzer Caroline C Lucchi Géraldine G Ducoroy Patrick P Falson Pierre P Savary Stéphane S Trompier Doriane D
The Journal of biological chemistry 20170303 17
ABCD1 and its homolog ABCD2 are peroxisomal ATP-binding cassette (ABC) half-transporters of fatty acyl-CoAs with both distinct and overlapping substrate specificities. Although it is established that ABC half-transporters have at least to dimerize to generate a functional unit, functional equivalents of tetramers (<i>i.e.</i> dimers of full-length transporters) have also been reported. However, oligomerization of peroxisomal ABCD transporters is incompletely understood but is of potential signif ...[more]