Severe mortality impact of the 1957 influenza pandemic in Chile.

ABSTRACT:

Introduction

Epidemiological studies of the 1957 influenza pandemic are scarce, particularly from lower-income settings.

Methods

We analyzed the spatial-temporal mortality patterns of the 1957 influenza pandemic in Chile, including detailed age-specific mortality data from a large city, and investigated risk factors for severe mortality impact across regions.

Results

Chile exhibited two waves of excess mortality in winter 1957 and 1959 with a cumulative excess mortality rate of 12 per 10 000, and a ~10-fold mortality difference across provinces. High excess mortality rates were associated with high baseline mortality (R² =41.8%; P=.02), but not with latitude (P>.7). Excess mortality rates increased sharply with age. Transmissibility declined from R=1.4-2.1

SUBMITTER: Chowell G 

PROVIDER: S-EPMC5410718 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature