Ontology highlight
ABSTRACT:
SUBMITTER: Urfer SR
PROVIDER: S-EPMC5411365 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Urfer Silvan R SR Kaeberlein Tammi L TL Mailheau Susan S Bergman Philip J PJ Creevy Kate E KE Promislow Daniel E L DEL Kaeberlein Matt M
GeroScience 20170403 2
Age is the single greatest risk factor for most causes of morbidity and mortality in humans and their companion animals. As opposed to other model organisms used to study aging, dogs share the human environment, are subject to similar risk factors, receive comparable medical care, and develop many of the same age-related diseases humans do. In this study, 24 middle-aged healthy dogs received either placebo or a non-immunosuppressive dose of rapamycin for 10 weeks. All dogs received clinical and ...[more]