Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions.
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ABSTRACT:
SUBMITTER: Mege RM
PROVIDER: S-EPMC5411698 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Publications
Integration of Cadherin Adhesion and Cytoskeleton at <i>Adherens</i> Junctions.
Mège René Marc RM Ishiyama Noboru N
Cold Spring Harbor perspectives in biology 20170501 5
The cadherin-catenin adhesion complex is the key component of the intercellular <i>adherens</i> junction (AJ) that contributes both to tissue stability and dynamic cell movements in epithelial and nonepithelial tissues. The cadherin adhesion complex bridges neighboring cells and the actin-myosin cytoskeleton, and thereby contributes to mechanical coupling between cells which drives many morphogenetic events and tissue repair. Mechanotransduction at cadherin adhesions enables cells to sense, sign ...[more]
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