Outcomes Associated With Antimicrobial De-escalation of Treatment for Pneumonia Within the Veterans Healthcare Administration.
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ABSTRACT:
SUBMITTER: Bohan JG
PROVIDER: S-EPMC5414017 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
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Outcomes Associated With Antimicrobial De-escalation of Treatment for Pneumonia Within the Veterans Healthcare Administration.
Bohan Jefferson G JG Remington Richard R Jones Makoto M Samore Matthew M Madaras-Kelly Karl K
Open forum infectious diseases 20161210 1
De-escalation, an antimicrobial stewardship concept, involves narrowing broad-spectrum empiric antimicrobial therapy based on clinical data. Current health outcomes evidence is lacking to support de-escalation. Studying Veterans Healthcare Administration pneumonia patients, de-escalation was associated with improved length of stay without affecting 30-day readmission or 30-day <i>Clostridium difficile</i> infection rates. ...[more]
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