Ontology highlight
ABSTRACT:
SUBMITTER: Takayama K
PROVIDER: S-EPMC5414778 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Takayama Ken-Ichi K Suzuki Takashi T Tsutsumi Shuichi S Fujimura Tetsuya T Takahashi Satoru S Homma Yukio Y Urano Tomohiko T Aburatani Hiroyuki H Inoue Satoshi S
Molecular endocrinology (Baltimore, Md.) 20141201 12
The transcriptional network of the androgen receptor (AR), a key molecule of prostate cancer, is frequently modulated by interactions with other transcriptional factors such as forkhead box protein A1 (FOXA1). However, global regulatory mechanisms of AR signaling mediated by such factors have not been well investigated. Here we conducted a chromatin immunoprecipitation sequence analysis, which revealed that another FOX family, FOXP1, is specifically regulated by both AR and FOXA1. We also found ...[more]