Ontology highlight
ABSTRACT:
SUBMITTER: Dias SA
PROVIDER: S-EPMC5415599 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Dias Susana A SA Freire João M JM Pérez-Peinado Clara C Domingues Marco M MM Gaspar Diana D Vale Nuno N Gomes Paula P Andreu David D Henriques Sónia T ST Castanho Miguel A R B MARB Veiga Ana S AS
Frontiers in microbiology 20170504
The increasing prevalence of multidrug-resistant bacteria urges the development of new antibacterial agents. With a broad spectrum activity, antimicrobial peptides have been considered potential antibacterial drug leads. Using bioinformatic tools we have previously shown that viral structural proteins are a rich source for new bioactive peptide sequences, namely antimicrobial and cell-penetrating peptides. Here, we test the efficacy and mechanism of action of the most promising peptides among th ...[more]