Ontology highlight
ABSTRACT:
SUBMITTER: Rodriguez Cruz SI
PROVIDER: S-EPMC5417640 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
PloS one 20170504 5
Among the adaptations of aquatic species during evolution of terrestrial tetrapods was the development of an epidermis preventing desiccation. In present day mammals, keratinocytes of the epidermis, using a membrane-bound transglutaminase (Tgm1), accomplish this function by synthesizing a scaffold of cross-linked protein to which a lipid envelope is attached. This study characterizes the abilities of two homologous transglutaminase isozymes in the teleost fish tilapia to form cross-linked protei ...[more]