Ontology highlight
ABSTRACT:
SUBMITTER: Farber PJ
PROVIDER: S-EPMC5425744 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Farber Patrick J PJ Mittermaier Anthony A
Biophysical reviews 20150221 2
Allosteric transmission of information between distant sites in biological macromolecules often involves collective transitions between active and inactive conformations. Nuclear magnetic resonance (NMR) spectroscopy can yield detailed information on these dynamics. In particular, relaxation dispersion techniques provide structural, dynamic, and mechanistic information on conformational transitions occurring on the millisecond to microsecond timescales. In this review, we provide an overview of ...[more]