Ontology highlight
ABSTRACT:
SUBMITTER: Hall SM
PROVIDER: S-EPMC5425951 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Hall Samantha M SM Coulter Sherry J SJ Knudsen Gabriel A GA Sanders J Michael JM Birnbaum Linda S LS
Toxicology letters 20170312
Tetrabromobisphenol A (TBBPA) is a brominated flame retardant used globally at high volumes, primarily in the epoxy resin of circuit boards. It has been detected in the environment and in humans. The National Toxicology Program found that chronic oral TBBPA treatment of 250mg/kg and higher caused an increased incidence of uterine lesions in female Wistar Han rats. The present laboratory has previously reported changes in gene expression associated with estrogen homeostasis in liver and uterine t ...[more]