Ontology highlight
ABSTRACT:
SUBMITTER: Djenoune L
PROVIDER: S-EPMC5428266 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Djenoune Lydia L Desban Laura L Gomez Johanna J Sternberg Jenna R JR Prendergast Andrew A Langui Dominique D Quan Feng B FB Marnas Hugo H Auer Thomas O TO Rio Jean-Paul JP Del Bene Filippo F Bardet Pierre-Luc PL Wyart Claire C
Scientific reports 20170407 1
Chemical and mechanical cues from the cerebrospinal fluid (CSF) can affect the development and function of the central nervous system (CNS). How such cues are detected and relayed to the CNS remains elusive. Cerebrospinal fluid-contacting neurons (CSF-cNs) situated at the interface between the CSF and the CNS are ideally located to convey such information to local networks. In the spinal cord, these GABAergic neurons expressing the PKD2L1 channel extend an apical extension into the CSF and an as ...[more]