Ontology highlight
ABSTRACT:
SUBMITTER: Veres TZ
PROVIDER: S-EPMC5429620 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Veres Tibor Z TZ Kopcsányi Tamás T Tirri Marko M Braun Armin A Miyasaka Masayuki M Germain Ronald N RN Jalkanen Sirpa S Salmi Marko M
Scientific reports 20170406 1
The mucosal layer of conducting airways is the primary tissue exposed to inhaled microorganisms, allergens and pollutants. We developed an in vivo two-photon microscopic approach that allows performing dynamic imaging studies in the mouse trachea, which is a commonly used in vivo model of human small-diameter bronchi. By providing stabilized access to the tracheal mucosa without intubation, our setup uniquely allows dynamic in vivo imaging of mucociliary clearance and steady-state immune cell be ...[more]