Ontology highlight
ABSTRACT:
SUBMITTER: Marisi G
PROVIDER: S-EPMC5431064 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Marisi Giorgia G Scarpi Emanuela E Passardi Alessandro A Nanni Oriana O Ragazzini Angela A Valgiusti Martina M Casadei Gardini Andrea A Neri Luca Maria LM Frassineti Giovanni Luca GL Amadori Dino D Ulivi Paola P
Scientific reports 20170502 1
Novel predictive biomarkers are needed to improve patient selection and optimize the use of bevacizumab (B) in metastatic colorectal cancer. We analyzed the potential of five circulating biomarkers to predict B efficacy and monitor response. Peripheral blood samples collected at baseline, at the first clinical evaluation and at progression were available for 129 patients enrolled in the prospective multicentric ITACa trial and randomized to receive FOLFOX4/FOLFIRI (CT) with (64 patients) or with ...[more]