Ontology highlight
ABSTRACT:
SUBMITTER: Snyder PJ
PROVIDER: S-EPMC5433755 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Snyder Peter J PJ Kopperdahl David L DL Stephens-Shields Alisa J AJ Ellenberg Susan S SS Cauley Jane A JA Ensrud Kristine E KE Lewis Cora E CE Barrett-Connor Elizabeth E Schwartz Ann V AV Lee David C DC Bhasin Shalender S Cunningham Glenn R GR Gill Thomas M TM Matsumoto Alvin M AM Swerdloff Ronald S RS Basaria Shehzad S Diem Susan J SJ Wang Christina C Hou Xiaoling X Cifelli Denise D Dougar Darlene D Zeldow Bret B Bauer Douglas C DC Keaveny Tony M TM
JAMA internal medicine 20170401 4
<h4>Importance</h4>As men age, they experience decreased serum testosterone concentrations, decreased bone mineral density (BMD), and increased risk of fracture.<h4>Objective</h4>To determine whether testosterone treatment of older men with low testosterone increases volumetric BMD (vBMD) and estimated bone strength.<h4>Design, setting, and participants</h4>Placebo-controlled, double-blind trial with treatment allocation by minimization at 9 US academic medical centers of men 65 years or older w ...[more]