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Copper (II)-doped semiconducting polymer dots for nitroxyl imaging in live cells.

ABSTRACT: The first nanoparticle-based fluorescent probe for the specific detection of nitroxyl (HNO) was designed and constructed by doping copper(II) into semiconducting polymer dots (Pdots). The probe turns on and fluoresces in the presence of HNO. We used the new sensor to monitor changes of HNO levels in live cells.

SUBMITTER: Wu X 

PROVIDER: S-EPMC5436714 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Copper (II)-doped semiconducting polymer dots for nitroxyl imaging in live cells.

Wu Xu X   Wu Li L   Wu I-Che IC   Chiu Daniel T DT  

RSC advances 20161026 105

The first nanoparticle-based fluorescent probe for the specific detection of nitroxyl (HNO) was designed and constructed by doping copper(II) into semiconducting polymer dots (Pdots). The probe turns on and fluoresces in the presence of HNO. We used the new sensor to monitor changes of HNO levels in live cells. ...[more]

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