Ontology highlight
ABSTRACT:
SUBMITTER: Kabza M
PROVIDER: S-EPMC5437911 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Kabza Michal M Karolak Justyna A JA Rydzanicz Malgorzata M Szcześniak Michał W MW Nowak Dorota M DM Ginter-Matuszewska Barbara B Polakowski Piotr P Ploski Rafal R Szaflik Jacek P JP Gajecka Marzena M
European journal of human genetics : EJHG 20170201 5
To understand better the factors contributing to keratoconus (KTCN), we performed comprehensive transcriptome profiling of human KTCN corneas for the first time using an RNA-Seq approach. Twenty-five KTCN and 25 non-KTCN corneas were enrolled in this study. After RNA extraction, total RNA libraries were prepared and sequenced. The discovery RNA-Seq analysis (in eight KTCN and eight non-KTCN corneas) was conducted first, after which the replication RNA-Seq experiment was performed on a second set ...[more]