Ontology highlight
ABSTRACT:
SUBMITTER: Brenowitz WD
PROVIDER: S-EPMC5438283 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Alzheimer's & dementia : the journal of the Alzheimer's Association 20161119 6
<h4>Introduction</h4>Whether co-occurring neuropathologies interact or independently affect clinical disease progression is uncertain. We estimated rates of clinical progression and tested whether associations between clinical progression and Alzheimer's disease neuropathology (ADNP) were modified by co-occurring Lewy body disease (LBD) or vascular brain injury (VBI).<h4>Methods</h4>Linear mixed effects models evaluated longitudinal trends in the Clinical Dementia Rating Scale Sum of Boxes on 20 ...[more]