Ontology highlight
ABSTRACT:
SUBMITTER: Lee AR
PROVIDER: S-EPMC5438622 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Lee Ahn R AR Li Yinan Y Xie Ning N Gleave Martin E ME Cox Michael E ME Collins Colin C CC Dong Xuesen X
Oncotarget 20170401 17
Although potent androgen receptor pathway inhibitors (ARPI) improve overall survival of metastatic prostate cancer patients, treatment-induced neuroendocrine prostate cancer (t-NEPC) as a consequence of the selection pressures of ARPI is becoming a more common clinical issue. Improved understanding of the molecular biology of t-NEPC is essential for the development of new effective management approaches for t-NEPC. In this study, we identify a splice variant of the MYST/Esa1-associated factor 6 ...[more]