Ontology highlight
ABSTRACT:
SUBMITTER: Gan Y
PROVIDER: S-EPMC6013970 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Gan Yu Y Li Yinan Y Long Zhi Z Lee Ahn R AR Xie Ning N Lovnicki Jessica M JM Tang Yuxin Y Chen Xiang X Huang Jiaoti J Dong Xuesen X
EBioMedicine 20180516
Treatment-induced neuroendocrine prostate cancer (t-NEPC) is an aggressive subtype of prostate cancer (PCa) that becomes more prevalent when hormonal therapy, chemotherapy, or radiation therapy is applied to patients with metastatic prostate adenocarcinoma (AdPC). How AdPC cells survive these anti-cancer therapies and progress into t-NEPC remains unclear. By comparing the whole transcriptomes between AdPC and t-NEPC, we identified Bif-1, an apoptosis-associated gene, which undergoes alternative ...[more]