Ontology highlight
ABSTRACT:
SUBMITTER: Verma D
PROVIDER: S-EPMC5444848 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Verma Deepshikha D Murmu Aruna A Gourinath Samudrala S Bhattacharya Alok A Chary Kandala V R KVR
PLoS pathogens 20170515 5
Cell cycle of Entamoeba histolytica, the etiological agent of amoebiasis, follows a novel pathway, which includes nuclear division without the nuclear membrane disassembly. We report a nuclear localized Ca2+-binding protein from E. histolytica (abbreviated hereafter as EhCaBP6), which is associated with microtubules. We determined the 3D solution NMR structure of EhCaBP6, and identified one unusual, one canonical and two non-canonical cryptic EF-hand motifs. The cryptic EF-II and EF-IV pair with ...[more]