Ontology highlight
ABSTRACT:
SUBMITTER: Goodman DB
PROVIDER: S-EPMC5445467 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Goodman Daniel B DB Kuznetsov Gleb G Lajoie Marc J MJ Ahern Brian W BW Napolitano Michael G MG Chen Kevin Y KY Chen Changping C Church George M GM
Genome biology 20170525 1
Inexpensive DNA sequencing and advances in genome editing have made computational analysis a major rate-limiting step in adaptive laboratory evolution and microbial genome engineering. We describe Millstone, a web-based platform that automates genotype comparison and visualization for projects with up to hundreds of genomic samples. To enable iterative genome engineering, Millstone allows users to design oligonucleotide libraries and create successive versions of reference genomes. Millstone is ...[more]