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A microchip electrophoresis-based fluorescence signal amplification strategy for highly sensitive detection of biomolecules.

ABSTRACT: We have developed a microchip electrophoresis (MCE)-based fluorescence signal amplification strategy as a universal MCE method for the detection of trace biomolecules. This strategy exhibits high sensitivity and specificity for target molecules, and has been applied for the detection of interferon-gamma (IFN-?) in human plasma with satisfactory results.

SUBMITTER: Qin Y 

PROVIDER: S-EPMC5446791 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature

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A microchip electrophoresis-based fluorescence signal amplification strategy for highly sensitive detection of biomolecules.

Qin Yingfeng Y   Zhang Liangliang L   Li Shuting S   Zhao Jingjin J   Huang Yong Y   Zhao Shulin S   Liu Yi-Ming YM  

Chemical communications (Cambridge, England) 20161201 2

We have developed a microchip electrophoresis (MCE)-based fluorescence signal amplification strategy as a universal MCE method for the detection of trace biomolecules. This strategy exhibits high sensitivity and specificity for target molecules, and has been applied for the detection of interferon-gamma (IFN-γ) in human plasma with satisfactory results. ...[more]

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