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Electrophoresis separation assisted G-quadruplex DNAzyme-based chemiluminescence signal amplification strategy on a microchip platform for highly sensitive detection of microRNA.

ABSTRACT: We have developed an electrophoresis separation assisted G-quadruplex DNAzyme-based chemiluminescence (CL) signal amplification strategy on a microchip platform for the detection of trace microRNA. This strategy exhibits high sensitivity and specificity for detection of target molecules.

SUBMITTER: Li J

PROVIDER: S-EPMC5079828 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature

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Electrophoresis separation assisted G-quadruplex DNAzyme-based chemiluminescence signal amplification strategy on a microchip platform for highly sensitive detection of microRNA.

Li Jian J Zhao Jingjin J Li Shuting S Zhang Liangliang L Huang Yong Y Zhao Shulin S Liu Yi-Ming YM

Chemical communications (Cambridge, England) 20161001 87

We have developed an electrophoresis separation assisted G-quadruplex DNAzyme-based chemiluminescence (CL) signal amplification strategy on a microchip platform for the detection of trace microRNA. This strategy exhibits high sensitivity and specificity for detection of target molecules. ...[more]

PMID: 27711307

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