Ontology highlight
ABSTRACT:
SUBMITTER: Prat A
PROVIDER: S-EPMC5449267 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Prat Aleix A Lluch Ana A Turnbull Arran K AK Dunbier Anita K AK Calvo Lourdes L Albanell Joan J de la Haba-Rodríguez Juan J Arcusa Angels A Chacón José Ignacio JI Sánchez-Rovira Pedro P Plazaola Arrate A Muñoz Montserrat M Paré Laia L Parker Joel S JS Ribelles Nuria N Jimenez Begoña B Bin Aiderus Abdul Aziz AA Caballero Rosalía R Adamo Barbara B Dowsett Mitch M Carrasco Eva E Martín Miguel M Dixon J Michael JM Perou Charles M CM Alba Emilio E
Clinical cancer research : an official journal of the American Association for Cancer Research 20161130 12
<b>Purpose:</b> Hormone receptor-positive (HR<sup>+</sup>) breast cancer is clinically and biologically heterogeneous, and subgroups with different prognostic and treatment sensitivities need to be identified.<b>Experimental Design:</b> Research-based PAM50 subtyping and expression of additional genes was performed on 63 patients with HR<sup>+</sup>/HER2<sup>-</sup> disease randomly assigned to neoadjuvant multiagent chemotherapy versus endocrine therapy in a phase II trial. The biology associat ...[more]