Ontology highlight
ABSTRACT:
SUBMITTER: Al-Shamary DS
PROVIDER: S-EPMC5451370 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Al-Shamary Danah S DS Al-Alshaikh Monirah A MA Kheder Nabila Abdelshafy NA Mabkhot Yahia Nasser YN Badshah Syed Lal SL Badshah Syed Lal SL
Chemistry Central journal 20170531 1
<h4>Background</h4>The quinazoline are an important class of medicinal compounds that possess a number of biological activities like anticancer, anticonvulsant and antioxidant etc.<h4>Results</h4>We evaluated the previously synthesized quinazoline derivatives 1-3 for their anticancer activities against three cancer cell lines (HepG2, MCF-7, and HCT-116). Among the tested compounds, quinazolines 1 and 3 were found to be more potent than the standard drug Vinblastine against HepG2 and MCF-7 cell l ...[more]