The Development of Novel Near-Infrared (NIR) Tetraarylazadipyrromethene Fluorescent Dyes.

ABSTRACT: Novel structures of an near-infrared (NIR) tetraarylazadipyrromethene (aza-BODIPY) series have been prepared. We designed the core structure containing two amido groups at the para-position of the aromatic rings. The amido group was incorporated to secure insensitivity to pH and to ensure a bathochromic shift to the NIR region. Forty members of aza-BODIPY compounds were synthesized by substitution of the acetyl group with commercial amines on the alpha bromide. The physicochemical properties and photostability were investigated and the fluorescence emission maxima (745~755 nm) were found to be in the near infrared (NIR) range of fluorescence.

SUBMITTER: Lee SC 

PROVIDER: S-EPMC5452499 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature